Big, very changes coming to MobileMe?  Apple  stores online and off have discontinued the boxed version of the software it sells at retail.  MobileMe has also been removed from Apple’s online store. You can still however sign up for a free trial through the MobileMe website. Apple Insider reports that MobileMe have been declared “end of life” by Apple. I say next thing is a cloud based service that lets you stream music and movies. That would just change the industry over night.